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Physicochemical Profiling

Physiochemical Profiling is a crucial part of drug discovery mostly contributing to the drug characterization and optimization. Early assessment provides critical information on problems with absorption, disposition and formulation. At Aaranya Biosciences we provide In-silico simulations based upon them- outcomes can be predicted using the screening data.

Platforms used for assessment:

  • Computational estimates of pKa, Log P/Log D and polar surface areas along with molecular surface properties.
  • Equilibrium Solubility Measurements
  • Log P/Log D estimation using chromatographic techniques
  • Potentiometric Titration (pKa)
  • Substance stability testing





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